Author

I. Brito

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:metagenomics· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Singh· 1 shared B. Ransegnola· 1 shared B.-K. Cho· 1 shared D. Choe· 1 shared H. Shi· 1 shared H. Zhou· 1 shared H.-R. Hong· 1 shared I. De Vlaminck· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

A. Singh

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4 papers

Recent·Most cited

Host-microbiome protein-protein interactions capture mechanisms in human disease

H. Zhou, J. F. Beltran, I. Brito

The paper links microbiome-derived proteins to disease-associated human pathways using metagenomic and protein-protein interaction analyses.

bioRxiv · Sep 4, 2021Microbiology

A multifaceted cellular damage repair and prevention pathway promotes high level tolerance to β-lactam antibiotics

J.-H. Shin, D. Choe, B. Ransegnola, H.-R. Hong, I. Onyekwere, T. Cross, Q. Shi, B.-K. Cho, L. F. Westblade, I. Brito, T. Doerr

This study shows that the VxrAB system in Vibrio cholerae reduces β-lactam antibiotic toxicity by managing iron levels and oxidative damage, enhancing bacterial tolerance.

bioRxiv · Aug 6, 2020Microbiology

Organoid Polymer Functionality and Mode of Klebsiella Pneumoniae Membrane Antigen Presentation Regulates Ex Vivo Germinal Center Epigenetics in Young and Aged B Cells

P. L. Graney, K. Lai, S. Post, I. Brito, J. Cyster, A. Singh

The paper develops PEG-organoids to study how polymer chemistry and antigen presentation affect germinal center-like B cell epigenetics in young and aged mice.

bioRxiv · Feb 16, 2020Immunology

Highly Multiplexed Spatial Mapping of Microbial Communities

H. Shi, W. Zipfel, I. Brito, I. De Vlaminck

The paper introduces HiPR-FISH, a method to map microbial communities with high spatial and taxonomic resolution, demonstrating its ability to distinguish multiple E. coli strains and reveal spatial structures in human and mouse microbiomes.

bioRxiv · Jun 21, 2019Microbiology