Author

J. D. Minna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 5 Research Focus:cell type annotation· 5 Organism:human· 5 Research Focus:differential expression· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

L. Girard· 3 shared A. F. Gazdar· 2 shared J. E. Johnson· 2 shared R. K. Kollipara· 2 shared A. Aloma· 1 shared A. Augustyn· 1 shared A. Luna· 1 shared A. Martin-Vega· 1 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCancer Biology

L. Girard

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 15, 2023

ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers

A. Martin-Vega, S. Earnest, A. Augustyn…·M. H. Cobb

This study identifies the ASCL1-DUSP6-ERK1/2 axis as a mechanism promoting survival in neuroendocrine lung cancers, suggesting DUSP6 as a potential therapeutic target.

DOI 10.1101/2023.06.15.545148

humanbulk RNA-seq

Cancer BiologybioRxivPreprintAug 13, 2020

Lineage transcription factors co-regulate subtype-specific genes providing a roadmap for systematic identification of small cell lung cancer vulnerabilities

K. Pozo, R. K. Kollipara, D. P. Kelenis…·J. E. Johnson

This study identifies lineage transcription factors and super-enhancer signatures in SCLC, revealing co-regulation of subtype-specific genes and highlighting ASCL1 as a key dependency.

DOI 10.1101/2020.08.13.249029

humanbulk RNA-seq

Cancer BiologybioRxivJul 28, 2020

Relationship Between Neuroendocrine and Immune Gene Expression in Small Cell Lung Cancer

L. Cai, H. Liu, F. Huang…·A. F. Gazdar

This study examines the relationship between neuroendocrine and immune gene expression in SCLC, finding that variant SCLC tumors regain immune gene expression and exhibit higher tumor-immune interactions.

DOI 10.1038/s42003-021-01842-7

humanbulk RNA-seq

Cancer BiologybioRxivPreprintMay 28, 2020

Lung cancer models reveal SARS-CoV-2-induced EMT contributes to COVID-19 pathophysiology

C. A. Stewart, C. M. Gay, K. Ramkumar…·L. A. Byers

The paper investigates how SARS-CoV-2 infection induces epithelial-mesenchymal transition (EMT) in lung cancer models, leading to changes in gene expression and potential therapeutic targets.

DOI 10.1101/2020.05.28.122291

humanbulk RNA-seq

Cancer BiologybioRxivPreprintMar 9, 2020

SCLC_CellMiner: Integrated Genomics and Therapeutics Predictors of Small Cell Lung Cancer Cell Lines based on their genomic signatures

C. Tlemsani, L. Pongor, L. Girard…·Y. Pommier

SCLC_CellMiner provides an integrated resource of 118 SCLC cell lines with omics data and drug sensitivity, identifying molecular subtypes and therapeutic targets.

DOI 10.1101/2020.03.09.980623

humanbulk RNA-seq