J. E. Johnson

Photosynthetic acclimation mediates exponential growth of a desert plant in Death Valley summer

This study shows Tidestromia oblongifolia rapidly acclimates to extreme heat by altering gene expression, organellar dynamics, and photosynthesis.

ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers

This study identifies the ASCL1-DUSP6-ERK1/2 axis as a mechanism promoting survival in neuroendocrine lung cancers, suggesting DUSP6 as a potential therapeutic target.

Diverse Arctic lake sediment microbiota shape methane emission temperature sensitivity

This study shows that spatial variations in sediment microbiota influence methane emission temperature sensitivity in Arctic lakes.

VaxArray Immunoassay for the Multiplexed Quantification of Poliovirus D-Antigen

The paper develops a multiplexed immunoassay for rapid and accurate quantification of poliovirus D-antigen across all three serotypes, improving upon traditional ELISA methods.

Dominant and nondominant distal radius microstructure: predictors of asymmetry and effects of a unilateral mechanical loading intervention

This study examines bone structure asymmetry between dominant and nondominant forearms and evaluates the effects of mechanical loading on bone properties over 12 months.

ASCL1 represses a latent osteogenic program in small cell lung cancer in multiple cells of origin

This study shows ASCL1 represses a latent osteogenic program in SCLC, promoting tumor initiation and preventing differentiation into bone tumors.

Lineage transcription factors co-regulate subtype-specific genes providing a roadmap for systematic identification of small cell lung cancer vulnerabilities

This study identifies lineage transcription factors and super-enhancer signatures in SCLC, revealing co-regulation of subtype-specific genes and highlighting ASCL1 as a key dependency.

ASCL1 regulates neurodevelopmental transcription factors and cell cycle genes in glioblastoma

This study shows ASCL1 regulates key genes in glioblastoma, affecting cell proliferation and survival in a mouse model.

Distal Radius Microstructure and Finite Element Bone Strain Are Related to Site-Specific Mechanical Loading and Areal Bone Mineral Density in Premenopausal Women

This study examines how mechanical loading and areal bone mineral density (aBMD) influence bone strain and microstructure in premenopausal women.