Author
J. D. Wren
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2018-2022 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 16 mutual co-author links10 papers
Recent·Most cited
- Cancer BiologybioRxivPreprint
Blocking necroptosis reduces inflammation and tumor incidence in a mouse model of diet-induced hepatocellular carcinoma
DOI 10.1101/2022.08.03.502666 - Cell BiologybioRxiv
Four novel, immortal cell lines derived from embryos of Xenopus tropicalis
G. J. Gorbsky, J. R. Daum, H. Sapkota…·M. E. Horb
The paper describes the development of four immortal cell lines from Xenopus tropicalis embryos and characterizes their karyotype and transcriptome.
DOI 10.1098/rsob.220089 - Cell BiologybioRxivPreprint
The NOTCH3 Downstream Target HEYL Regulates Human Airway Epithelial Club Cell Differentiation
M. Bodas, B. Subramaniyan, A. R. Moore…·M. S. Walters
This study identifies HEYL as a downstream target of NOTCH3 that regulates human airway epithelial club cell differentiation through in vitro and in vivo analyses.
- Scientific Communication & EducationbioRxivPreprint
Detecting potential reference list manipulation within a citation network
The paper identifies potential reference list manipulation by analyzing citation patterns and using the Gini Index to detect skew, estimating 16% of authors may engage in it.
DOI 10.1101/2020.08.12.248369 - Cancer BiologybioRxiv
SEED-MEDIATED RNA INTERFERENCE OF ANDROGEN SIGNALING AND SURVIVAL NETWORKS INDUCES CELL DEATH IN PROSTATE CANCER CELLS
J. M. Corbin, C. Georgescu, J. D. Wren…·M. J. Ruiz Echevarria
The paper shows that specific small RNAs inhibit androgen signaling and induce cell death in prostate cancer cells by targeting AR-coregulatory genes through 3-UTR complementarity.
DOI 10.1016/j.omtn.2021.03.002 - ImmunologybioRxivPreprint
E proteins orchestrate dynamic transcriptional cascades to suppress ILC2 differentiation
V. Peng, C. Georgescu, A. Bakowska…·X.-H. Sun
This study identifies E proteins as suppressors of ILC2 differentiation by repressing a transcriptional network through upregulation of repressor genes.
DOI 10.1101/2020.03.26.008037 - Cell BiologybioRxiv
Neuroretinal-derived caveolin-1 promotes endotoxin-induced inflammation in the murine retina
J. Gurley, G. Gmyrek, M. E. McClellan…·M. H. Elliott
This study shows that neural retinal-derived caveolin-1 promotes inflammation in the murine retina, as its depletion reduces cytokine production and immune cell infiltration following LPS challenge.
DOI 10.1167/iovs.61.12.19 - Cell BiologybioRxiv
CSAG1 Maintains the Integrity of the Mitotic Centrosome in Cells with Defective p53
H. Sapkota, J. D. Wren, G. J. Gorbsky
The paper identifies CSAG1 as a novel mitotic component that maintains centrosome integrity, particularly in cells with defective p53.
DOI 10.1242/jcs.239723 - Cancer BiologybioRxiv
A Tumor Suppressor-Regulated Cell Cycle Derived Gene Signature Is Prognostic Of Recurrence Risk In Prostate Cancer
C. Georgescu, J. M. Corbin, S. Thivibilliers…·M. J. Ruiz Echevarria
The paper develops a gene signature based on Tmeff2-regulated cell cycle genes that predicts recurrence risk in prostate cancer and outperforms existing prognostic markers.
DOI 10.1186/s12885-019-5592-6