Modulation of SLFN11 induces changes in DNA Damage response
C. M. Raynaud, E. I. Ahmed, A. Jabeen, A. Sanchez, S. Sherif, T. C. Carneiro-Lobo, A. Awad, D. Awartani, A. Naik, R. Thomas, J. Decock, G. Zoppoli, D. Bedognetti, W. Hendrickx
This study shows that increasing SLFN11 expression through CRISPR-dCas9 systems enhances DNA damage response sensitivity in breast cancer cells.
bioRxiv · Apr 2, 2023 · PreprintCancer Biology