Author

M. Saad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

D. Bedognetti· 2 shared J. Galon· 2 shared J. Roelands· 2 shared M. Ceccarelli· 2 shared W. Hendrickx· 2 shared A. Cho· 1 shared A. Gazumyan· 1 shared B. Aydin· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

D. Bedognetti

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Suppression of epithelial proliferation and tumorigenesis by immunoglobulin A

G. P. Donaldson, G. L. Reis, M. Saad, C. Wichmann, I. Mamede, G. Chen, C. E. Harrer, N. L. DelGaudio, D. Zhang, B. Aydin, T. B. R. Castro, S. Grivennikov, B. S. Reis, E. Liu, S. C. Eisenbarth, , D. Mucida

This study shows that IgA suppresses epithelial proliferation and tumorigenesis by interacting with DMBT1, highlighting its role in maintaining mucosal homeostasis.

bioRxiv · Oct 6, 2023 · PreprintImmunology

Longitudinal clonal dynamics of HIV-1 latent reservoirs measured by combination quadruplex polymerase chain reaction and sequencing

A. Cho, C. Gaebler, T. Olveira, V. Ramos, M. Saad, J. Lorenzi, A. Gazumyan, S. Moir, T.-W. Chun, M. Caskey, M. Nussenzweig

This study uses Q4PCR to measure longitudinal changes in HIV-1 latent reservoirs, finding that intact proviruses decay faster than defective ones and show increased clonal expansion over time.

bioRxiv · Oct 28, 2021Immunology

Germline genetic contribution to the immune landscape of cancer

R. W. Sayaman, M. Saad, V. Thorsson, W. Hendrickx, J. Roelands, Y. Mokrab, F. Farshidfar, T. Kirchhoff, R. F. Sweis, O. F. Bathe, E. Porta-Pardo, M. J. Campbell, C. Stretch, D. Hu, S. Huntsman, , D. Bedognetti

This study identifies germline genetic variants associated with immune traits in cancer, revealing their impact on the tumor immune microenvironment.

bioRxiv · Jan 30, 2020Immunology

Identification of two aptamers binding to Legionella pneumophila with high affinity and specificity

M. Saad, M. Tabrizian, D. Chinerman, S. P. Faucher

This study identifies two aptamers that bind to Legionella pneumophila with high affinity and specificity, enabling potential use in biosensors for rapid detection.

bioRxiv · Dec 13, 2019Microbiology

Genomic landscape of tumor-host interactions with differential prognostic and predictive connotations

J. Roelands, W. Hendrickx, P. J. K. Kuppen, R. Mall, G. Zoppoli, M. Saad, K. Halliwill, G. Curigliano, D. Rinchai, J. Decock, L. Delogu, T. Turan, J. Samayoa, L. Chouchane, E. Wang, , D. Bedognetti

The paper analyzes tumor-host interactions across 31 cancer types using the ICR signature to identify prognostic and predictive implications of immune phenotypes.

bioRxiv · May 8, 2019Cancer Biology