Author

J. Desponds

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:Drosophila· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

A. M. Walczak· 2 shared A. Mayer· 2 shared C. A. Perez Romero· 1 shared C. Fradin· 1 shared G. Reddy· 1 shared H. Tran· 1 shared I. Nemenman· 1 shared M. Carballo-Pacheco· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

A. M. Walczak

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Author profile →

4 papers

Recent·Most cited

Early life imprints the hierarchy of T cell clone sizes

M. U. Gaimann, M. Nguyen, J. Desponds, A. Mayer

This study shows that early life clonal expansions shape the long-term hierarchy of T cell clone sizes in humans, even after decades of aging.

bioRxiv · Jul 21, 2020Immunology

hunchback promoters can readout morphogenetic positional information in less than a minute

J. Desponds, M. Vergassola, A. M. Walczak

The paper shows that hunchback promoters can make accurate cell fate decisions within minutes by dynamically updating likelihoods of anterior/posterior positions based on Bicoid morphogen concentration.

bioRxiv · Jun 22, 2019Biophysics

Receptor crosstalk improves concentration sensing of multiple ligands

M. Carballo-Pacheco, J. Desponds, T. Gravilchenko, A. Mayer, R. Prizak, G. Reddy, I. Nemenman, T. Mora

This study shows that receptor crosstalk can enhance precision in sensing multiple ligand concentrations by utilizing non-cognate ligand binding events.

bioRxiv · Oct 20, 2018Cell Biology

Precision in a rush: trade-offs between reproducibility and steepness of the hunchback expression pattern

H. Tran, J. Desponds, C. A. Perez Romero, M. Coppey, C. Fradin, N. Dostatni, A. M. Walczak

The paper examines how short developmental cycles affect the precision and reproducibility of hunchback gene expression patterns in flies.

bioRxiv · Sep 27, 2018Biophysics