Author

M. Coppey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5 Cell Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 8 Approach:experimental assay· 7 Research Focus:development & morphogenesis· 5 Assay:imaging· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

S. De Beco· 3 shared G. Cornilleau· 2 shared J. de Seze· 2 shared K. Vaidziulyte· 2 shared M. Bongaerts· 2 shared M. Dahan· 2 shared R. Voituriez· 2 shared A. Battistella· 1 shared

Activity by Year

2017-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersBiophysics

S. De Beco

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion

J. de Seze, M. Bongaerts, B. Boulevard, M. Coppey

The paper uses optogenetics to control RhoA GEF localization, showing a single protein can induce retraction or protrusion based on its concentration, revealing a signaling switch mechanism.

eLife · May 27, 2025Peer-reviewedCell Biology

Two timescales control the creation of large protein aggregates in cells

A. Movilla Miangolarra, A. Duperray-Susini, M. Coppey, M. Castellana

The paper studies protein aggregation in cells, identifying two timescales that control aggregate size and number, with implications for disease and spatial organization.

bioRxiv · Apr 1, 2021Biophysics

Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking

K. Vaidziulyte, A.-S. Mace, A. Battistella, W. Beng, K. Schauer, M. Coppey

This study shows that persistent cell migration results from the interplay between protrusion dynamics and polarized trafficking, demonstrated through live-cell imaging and optogenetic experiments.

bioRxiv · Mar 20, 2021Biophysics

Parallelized manipulation of adherent living cells by magnetic nanoparticles-mediated forces

M. Bongaerts, K. Aizel, E. Secret, A. Jan, T. Nahar, F. Raudzus, S. Neumann, N. Telling, R. Heumann, J.-M. Siaugue, C. Menager, J. Fresnais, C. Villard, A. El Haj, J. Piehler, , M. Coppey

This study demonstrates that magnetic nanoparticle-mediated forces from micro-magnetic pillars can direct cell migration and neurite outgrowth in adherent cells.

bioRxiv · Jul 21, 2020Bioengineering

Cell clusters adopt a collective amoeboid mode of migration in confined non-adhesive environments

D.-L. Pages, E. Dornier, J. de Seze, L. Wang, R. Luan, J. Cartry, C. Canet-Jourdan, J. Raingeaud, R. Voituriez, M. Coppey, M. Piel, F. Jaulin

The paper shows that cell clusters can migrate in a collective amoeboid mode without adhesion, relying on supracellular contractility rather than traction forces.

bioRxiv · May 28, 2020 · PreprintCell Biology

Precision in a rush: trade-offs between reproducibility and steepness of the hunchback expression pattern

H. Tran, J. Desponds, C. A. Perez Romero, M. Coppey, C. Fradin, N. Dostatni, A. M. Walczak

The paper examines how short developmental cycles affect the precision and reproducibility of hunchback gene expression patterns in flies.

bioRxiv · Sep 27, 2018Biophysics

Stick-slip dynamics of cell adhesion triggers spontaneous symmetry breaking and directional migration

K. Hennig, I. Wang, P. Moreau, L. Valon, S. De Beco, M. Coppey, Y. Miroshnikova, C. Albiges Rizo, C. Favard, R. Voituriez, m. Balland

Cells break symmetry through mechanical instabilities causing stochastic adhesion detachment, initiating migration without pre-established polarity.

bioRxiv · Jun 25, 2018Biophysics

Optogenetic dissection of Rac1 and Cdc42 gradient shaping

S. de Beco, K. Vaidziulyte, J. Manzi, F. Dalier, F. Di Frederico, G. Cornilleau, M. Dahan, M. Coppey

This study uses optogenetics and micropatterning to show that Cdc42 and Rac1 gradients in migrating cells are shaped by spatial patterns of activators and deactivators, not advection or diffusion, and that gradient extent, not slope or amplitude, controls cell migration.

bioRxiv · May 8, 2018Cell Biology

Gradients Of Rac1 Nanoclusters Support Spatial Patterns Of Rac1 Signaling

A. Remorino, S. De Beco, F. Cayrac, F. Di Federico, G. Cornilleau, A. Gautreau, M. C. Parrini, J.-B. Masson, M. Dahan, M. Coppey

The paper shows Rac1 forms nanoclusters that create spatial gradients supporting Rac1 activity patterns in cell migration.

bioRxiv · Apr 28, 2017Biophysics