Author

J. Doering

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:statistical model· 1

Frequent Co-Authors

N. J. Mantis· 4 shared G. Van Slyke· 2 shared O. Donini· 2 shared A. F. Richards· 1 shared C. Richardson· 1 shared D. B. Volkin· 1 shared D. Ehrbar· 1 shared D. J. Ehrbar· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersImmunology

N. J. Mantis

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4 papers

Recent·Most cited

Effects of aluminum-salt, CpG and emulsion adjuvants on the stability and immunogenicity of a virus-like particle displaying the SARS-CoV-2 receptor binding domain (RBD)

O. S. Kumru, S. Bajoria, K. Kaur, J. M. Hickey, G. Van Slyke, J. Doering, K. Berman, C. Richardson, H. Lien, H. Kleanthous, N. J. Mantis, S. B. Joshi, D. B. Volkin

This paper evaluates the stability and immunogenicity of a SARS-CoV-2 RBD VLP vaccine candidate formulated with different adjuvants and finds that AP and AH adjuvants provide comparable immunogenicity to AV, with AP showing higher neutralizing titers.

bioRxiv · Jul 10, 2023Immunology

Durable Immunity to Ricin Toxin Elicited by a Thermostable, Lyophilized Subunit Vaccine

H. Novak, J. Doering, D. Ehrbar, O. Donini, N. J. Mantis

This paper demonstrates that a two-dose regimen of RiVax provides durable protection against ricin toxin challenge in mice for up to one year.

bioRxiv · Sep 8, 2021Immunology

Endpoint and Epitope-specific Antibody Responses as Correlates of Vaccine-mediated Protection of Mice against Ricin Toxin

G. Van Slyke, D. J. Ehrbar, J. Doering, J. Yates, E. Vitetta, O. Donini, N. J. MANTIS

This paper develops a multivariate model using antibody endpoint titers and epitope-specific inhibition values to predict vaccine-mediated protection against ricin toxin in mice.

bioRxiv · May 6, 2020Immunology

Inhibition of Invasive Salmonella by Orally Administered IgA and IgG Monoclonal Antibodies

A. F. Richards, J. Doering, S. A. Lozito, J. Varrone, M. Pauly, K. Whaley, L. Zeitlin, N. J. Mantis

This study shows orally administered IgA and SIgA monoclonal antibodies can reduce Salmonella Typhimurium uptake in Peyers patches, while IgG is less effective, highlighting the need for improved formulations to sustain mAb activity in the gut.

bioRxiv · Sep 23, 2019Immunology