Author

A. F. Richards

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein sequence· 1

Frequent Co-Authors

N. J. Mantis· 2 shared A. Carfi· 1 shared B. R. Fritz· 1 shared C. E. Deal· 1 shared C. J. Hsiao· 1 shared D. Liu· 1 shared E. Narayanan· 1 shared H. Koch· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

N. J. Mantis

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2 papers

Recent·Most cited

mRNA delivery of dimeric human IgA protects mucosal tissues from bacterial infection

C. E. Deal, A. F. Richards, T. Yeung, M. J. Maron, Z. Wang, Y.-T. Lai, B. R. Fritz, S. Himansu, E. Narayanan, D. Liu, R. Koleva, S. Licht, C. J. Hsiao, I. L. Rajlic, H. Koch, , O. J. Plante

The paper demonstrates that mRNA-delivered human IgA can protect mucosal tissues from bacterial infection by trafficking to mucosal sites and limiting bacterial invasion.

bioRxiv · Jan 3, 2023 · PreprintImmunology

Inhibition of Invasive Salmonella by Orally Administered IgA and IgG Monoclonal Antibodies

A. F. Richards, J. Doering, S. A. Lozito, J. Varrone, M. Pauly, K. Whaley, L. Zeitlin, N. J. Mantis

This study shows orally administered IgA and SIgA monoclonal antibodies can reduce Salmonella Typhimurium uptake in Peyers patches, while IgG is less effective, highlighting the need for improved formulations to sustain mAb activity in the gut.

bioRxiv · Sep 23, 2019Immunology