The dynamic properties of a nuclear coactivator binding domain are evolutionarily conserved
E. Karlsson, F. A. Sorgenfrei, E. Andersson, J. Dogan, P. Jemth, c. chi
The paper compares the dynamic properties of an ancient NCBD from a bilaterian ancestor to human NCBD, finding conserved dynamics despite increased thermodynamic stability.
bioRxiv · Jun 10, 2021Biophysics