Author

F. A. Sorgenfrei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:multiple species· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Andersson· 2 shared E. Karlsson· 2 shared P. Jemth· 2 shared A. Erkelens· 1 shared C. Camilloni· 1 shared c. chi· 1 shared C. Paissoni· 1 shared J. Dogan· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiophysics

E. Andersson

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2 papers

Recent·Most cited

BiophysicsbioRxivJun 10, 2021

The dynamic properties of a nuclear coactivator binding domain are evolutionarily conserved

E. Karlsson, F. A. Sorgenfrei, E. Andersson…·c. chi

The paper compares the dynamic properties of an ancient NCBD from a bilaterian ancestor to human NCBD, finding conserved dynamics despite increased thermodynamic stability.

DOI 10.1038/s42003-022-03217-y

experimental assayprotein folding & dynamics

𝕏 PostBluesky

BiophysicsbioRxivMar 27, 2020

Evolution of an interaction between disordered proteins resulted in increased heterogeneity of the binding transition state

E. Karlsson, C. Paissoni, A. Erkelens…·P. Jemth

The paper compares the binding transition states of ancestral and human IDP domains, finding increased heterogeneity in the human complex.

DOI 10.1074/jbc.ra120.015645

humanmultiple species

𝕏 PostBluesky