Author

J. Dresser

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. C. Kimmelman· 1 shared A. Myers· 1 shared B. N. Nicolay· 1 shared B. S. Nelson· 1 shared C. A. Lyssiotis· 1 shared C. Cotta-Ramusino· 1 shared C. J. Halbrook· 1 shared C. M. Sousa· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. C. Kimmelman

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1 paper

Recent·Most cited

Cancer BiologyCancer & MetabolismPeer-reviewedJan 2, 2020

Tissue of Origin Dictates GOT1 Dependence and Confers Synthetic Lethality to Radiotherapy

B. S. Nelson, L. Lin, D. M. Kremer…·C. A. Lyssiotis

The paper shows that pancreatic ductal adenocarcinoma (PDA) is more dependent on GOT1 than colorectal cancer (CRC) and that GOT1 inhibition synergizes with radiotherapy to inhibit PDA growth.

DOI 10.1186/s40170-019-0202-2

humanbulk RNA-seq

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