J. E. Pool

The Precision and Power of Population Branch Statistics in Identifying the Genomic Signatures of Local Adaptation

This study compares population branch statistics to FST in detecting local selective sweeps, finding branch statistics more accurate and specific under various evolutionary models.

Recombinant inbred line panels inform the genetic architecture and interactions of adaptive traits in Drosophila melanogaster

This study uses Drosophila melanogaster recombinant inbred lines to analyze the genetic architecture and interactions of adaptive traits, finding detectable alleles and gene-by-environment interactions but limited epistasis.

Courtship song differs between African and European populations of Drosophila melanogaster and involves a strong effect locus

The paper identifies a strong genetic locus influencing courtship song differences between African and European Drosophila melanogaster populations.

Polygenic architecture of adaptation to a high-altitude environment for Drosophila melanogaster wing shape and size.

This study identifies a polygenic architecture for wing shape and size adaptation in Drosophila melanogaster to high-altitude environments, with one large-effect QTL and many small-effect alleles contributing to divergence.

Inversions Can Accumulate Balanced Sexual Antagonism: Evidence from Simulations and Drosophila Experiments

This paper uses simulations and Drosophila experiments to show that chromosomal inversions can maintain polymorphism through sex-specific fitness tradeoffs and antagonistic pleiotropy.

Genomic Diversity Illuminates the Environmental Adaptation of Drosophila suzukii

This study uses whole-genome sequencing to analyze genomic diversity and environmental adaptation of Drosophila suzukii across 29 populations, identifying genetic signals linked to environmental factors.

Genomes From 25 Historical Drosophila melanogaster Specimens Illuminate Adaptive and Demographic Changes Across More Than 200 Years of Evolution

This study sequenced 25 historical Drosophila melanogaster genomes to analyze adaptive and demographic changes over 200 years, identifying selection signals and population dynamics.

Hybrid Breakdown in Male Reproduction Between Recently-Diverged Drosophila melanogaster Populations Has a Complex and Variable Genetic Architecture

This study investigates hybrid breakdown in recently-diverged Drosophila melanogaster populations, finding complex genetic incompatibilities affecting male reproduction but not female viability.

Gene regulatory evolution in cold-adapted fly populations neutralizes plasticity and may undermine genetic canalization

This study examines how adaptive evolution in cold-adapted Drosophila populations affects gene regulatory plasticity and canalization, finding that adaptive changes neutralize ancestral plasticity and may reduce genetic canalization for gene expression but not splicing.

SNP-level FST outperforms window statistics for detecting soft sweeps in local adaptation

This study compares SNP-level FST and window-based statistics for detecting soft sweeps in local adaptation, finding SNP FST more effective for complete or mostly complete sweeps.

A Population Genomic Assessment of Three Decades of Evolution in a Natural Drosophila Population

This study analyzes genome-wide allele frequency changes in Drosophila melanogaster over 35 years to assess evolutionary forces and adaptation.

Interactions between natural selection and recombination shape the genomic landscape of introgression

The paper investigates how natural selection and recombination influence introgression patterns in Drosophila melanogaster, finding that selection can reverse the typical positive correlation between introgression and recombination.

The Evolution of Larger Size in High Altitude Drosophila melanogaster has a Polymorphic Genetic Architecture

The paper investigates the genetic basis of larger body size in high altitude Drosophila melanogaster using QTL mapping and finds a polygenic architecture with moderate effect loci and no complete fixation of causative variants.

Parallel and Population-specific Gene Regulatory Evolution in Cold-Adapted Fly Populations

The paper examines gene regulatory evolution in cold-adapted Drosophila populations, finding parallel expression changes and varying cis-trans regulatory contributions across populations.

Impacts of Recurrent Hitchhiking on Divergence and Demographic Inference in Drosophila

The paper evaluates how recurrent hitchhiking models affect genetic divergence and demographic inference in Drosophila, finding biases in parameter estimation but some utility for recently diverged populations.