Author

J. Lack

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

A. B. F. Barletta· 1 shared C. Barillas-Mury· 1 shared C. Meneses· 1 shared E. Iniguez· 1 shared F. Oliveira· 1 shared G. Hoppel· 1 shared I. V. Coutinho-Abreu· 1 shared J. Andersen· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

A. B. F. Barletta

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Genetic exchange in Leishmania is facilitated by IgM natural antibodies

T. D. Serafim, E. Iniguez, A. B. F. Barletta, J. S. P. Doehl, M. Short, J. Lack, P. Cecilio, V. Nair, M. Disotuar, T. Wilson, I. V. Coutinho-Abreu, F. Oliveira, C. Meneses, C. Barillas-Mury, J. Andersen, , J. G. Valenzuela

This study shows IgM antibodies facilitate Leishmania genetic hybridization in vitro and in vivo, leading to full genome hybrids and increased genetic exchange.

bioRxiv · Jun 9, 2022 · PreprintMicrobiology

Gene regulatory evolution in cold-adapted fly populations neutralizes plasticity and may undermine genetic canalization

Y. Huang, J. Lack, G. Hoppel, J. E. Pool

This study examines how adaptive evolution in cold-adapted Drosophila populations affects gene regulatory plasticity and canalization, finding that adaptive changes neutralize ancestral plasticity and may reduce genetic canalization for gene expression but not splicing.

bioRxiv · Jan 14, 2022Evolutionary Biology