Cell BiologybioRxivPreprint
Telomerase deficiency in humans is associated with systemic age-related changes in energy metabolism
E. N. James, V. Sagi-Kiss, M. Bennett…·E. K. Parkinson
This study identifies systemic metabolic changes in telomerase-deficient patients, showing that pyruvate and lactate levels distinguish Dyskeratosis Congenita from controls, suggesting metabolic shifts linked to telomere dysfunction.
DOI 10.1101/2022.02.28.481982