M. Bennett

Dual Mechanism of Action: Exosomes from Human iPSC-Cardiomyocytes and Mesenchymal Stem Cells Restore Injured Myocardium

This study shows that exosomes from human iPSC-cardiomyocytes and mesenchymal stem cells improve heart function after myocardial infarction in pigs, with distinct miRNA mechanisms.

ROS responsive Aux/IAA multimerization modulates auxin responses

The paper shows ROS-induced IAA3/SHY2 multimerization regulates auxin responses during xerobranching and lateral root emergence in plants.

Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus

The paper tests British wildlife for SARS-CoV-2 and finds no infections but identifies a new minacovirus in stoats.

Sarbecoviruses of British Horseshoe Bats; Sequence Variation and Epidemiology

The paper tests for sarbecoviruses in British horseshoe bats, finding widespread infection in R. hipposideros but not R. ferrumequinum, and no evidence of human-to-bat transmission.

Integration of synthetic microbial consortia based bioprocessing with pyrolysis for efficient conversion of cellulose to valuables

This paper integrates synthetic microbial consortia-based bioprocessing with pyrolysis to convert cellulose into chemicals and biofuels, achieving high product yields.

Mesenchymal Stromal Cells Donate Mitochondria to Articular Chondrocytes Exposed to Mitochondrial, Environmental, and Mechanical Stress

This paper shows that mesenchymal stromal cells transfer mitochondria to stressed chondrocytes in vitro and in situ, offering a new therapeutic strategy for osteoarthritis.

Telomerase deficiency in humans is associated with systemic age-related changes in energy metabolism

This study identifies systemic metabolic changes in telomerase-deficient patients, showing that pyruvate and lactate levels distinguish Dyskeratosis Congenita from controls, suggesting metabolic shifts linked to telomere dysfunction.

Computer-Assisted Mitotic Count Using a Deep Learning-based Algorithm Improves Inter-Observer Reproducibility and Accuracy in canine cutaneous mast cell tumors

Genome-scale metabolic modelling of P. thermoglucosidasius NCIMB 11955 reveals metabolic bottlenecks in anaerobic metabolism.

This paper develops a genome-scale metabolic model for P. thermoglucosidasius to identify metabolic bottlenecks and guide metabolic engineering.

A multiplexed work-flow for absolute quantification of Klebsiella oxytoca Nif proteins

This study develops a high-throughput pipeline to quantify all twenty Nif proteins in Klebsiella oxytoca using MRM-MS and QconCAT standards, revealing temporal regulation and abundance disparities.

Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports its Classification as a Novel Species

A network of transcriptional repressors mediates auxin response specificity

The paper identifies a network of transcriptional repressors that regulate ARF activator gene expression in Arabidopsis thaliana, contributing to auxin response specificity.

Cell death in cells overlying lateral root primordia contributes to organ growth in Arabidopsis

The paper shows that cell death in cells overlying lateral root primordia in Arabidopsis contributes to organ growth, challenging the idea that plant organ growth relies solely on cell division.