Author

J. Garssen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Giovanazzi· 2 shared F. A. Redegeld· 2 shared M. H. M. Wauben· 2 shared M. I. Zonneveld· 2 shared M. Kleinjan· 2 shared A. F. M. Altelaar· 1 shared A. H. P. America· 1 shared A. J. A. M. Sijts· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

A. Giovanazzi

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Author profile →

5 papers

Recent·Most cited

Maternal allergic sensitization affects the T cell modulatory capacity and molecular cargo of milk derived extracellular vesicles

M. J. C. van Herwijnen, A. Giovanazzi, M. I. Zonneveld, J. J. Maqueda, M. Kleinjan, S. Goerdayal, F. Vollmy, A. van Bruggen - de Haan, T. A. P. Driedonks, G. J. A. Arkesteijn, R. M. van Elburg, G. N. van der Meulen, J. Garssen, C. Oliveira, A. F. M. Altelaar, , M. H. M. Wauben

This study examines how maternal allergic sensitization affects the function and molecular content of milk extracellular vesicles, finding that EVs from non-allergic mothers more strongly inhibit T cell activation.

bioRxiv · Aug 11, 2023 · PreprintImmunology

Raw milk kefir: microbiota, bioactive peptides, and immune modulation.

T. Baars, B. van Esch, L. van Ooijen, Z. Zhang, P. Dekker, S. Boeren, M. Diks, J. Garssen, K. Hettinga, R. Kort

This study characterizes the microbial and peptidomic composition of raw and heated milk kefir and shows that raw milk kefir suppresses allergic responses in mice.

bioRxiv · Oct 19, 2022Microbiology

Human Milk Oligosaccharide 2'-fucosyllactose inhibits ligand binding to C-type lectin DC-SIGN but not to Langerin

R. Mukherjee, V. J. Somovilla, F. Chiodo, S. Bruijns, R. J. Pieters, J. Garssen, Y. van Kooyk, J. v. BERGENHENEGOUWEN, A. Kraneveld

This study shows that 2'-fucosyllactose (2-FL) inhibits DC-SIGN ligand binding but not Langerin, with molecular dynamics revealing structural differences in binding modes.

bioRxiv · Jul 27, 2022Biochemistry

A combined microphysiological-computational omics approach in dietary protein evaluation

P. G. Jochems, W. R. Keusters, A. H. P. America, P. C. Rietveld, S. Bastiaan-Net, R. M. Ariens, M. M. M. Tomassen, F. Lewis, Y. Li, K. G. Westphal, J. Garssen, H. J. Wichers, J. Van Bergenhenegouwen, R. Masereeuw

This study evaluates dietary protein sources using a combined experimental and computational approach, showing that protein source type does not drive clustering of bioactive peptide delivery potential.

bioRxiv · Jul 3, 2020Bioengineering

Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses

M. I. Zonneveld, M. J. C. Herwijnen, M. M. Fernandez-Gutierrez, A. Giovanazzi, A. M. de Groot, M. Kleinjan, T. M. M. van Capel, A. J. A. M. Sijts, L. S. Taams, J. Garssen, E. C. de Jong, M. Kleerebezem, E. N. M. Nolte-'t Hoen, F. A. Redegeld, M. H. M. Wauben

bioRxiv · Apr 29, 2020Immunology