C. Oliveira

A proteogenomic pipeline for the analysis of protein biosynthesis errors in the human pathogen Candida albicans.

This study develops a proteogenomic pipeline to detect amino acid misincorporation in Candida albicans and shows increased misincorporation at CUG sites without affecting other codons.

Maternal allergic sensitization affects the T cell modulatory capacity and molecular cargo of milk derived extracellular vesicles

This study examines how maternal allergic sensitization affects the function and molecular content of milk extracellular vesicles, finding that EVs from non-allergic mothers more strongly inhibit T cell activation.

tRNASer overexpression induces adaptive mutations in NSCLC tumors

This study shows that overexpressing tRNASer in NSCLC tumors increases mutation burden and generates variants that promote proliferation and therapy resistance.

Accelerating manufacturing to start large-scale supply of a new adenovirus-vectored vaccine within 100 days

This paper describes an accelerated manufacturing process for adenovirus-vectored vaccines, enabling large-scale supply within 100 days of pathogen identification.

Epithelial-mesenchymal plasticity induced by discontinuous exposure to TGFβ1 promotes tumour growth

The paper shows that discontinuous TGFβ1 exposure induces EMT/MET transitions in EpH4 cells, leading to RE-cells with molecular and functional heterogeneity that promotes tumour growth.

Filamentation in Candida albicans is modulated by adaptive translation of farnesol signalling genes

This study shows that atypical CUG codon translation in Candida albicans modulates filamentation by altering farnesol production and Nrg1 repressor degradation.

Bacteriophages targeting Acinetobacter baumannii capsule induce antimicrobial resensitization

This study identifies phages targeting Acinetobacter baumannii capsule that induce antimicrobial resensitization by disrupting capsule biosynthesis and enhancing susceptibility to antibiotics and the immune system.

CD44v6 expression is a novel predictive marker of therapy response and poor prognosis in gastric cancer patients

This study identifies CD44v6 expression as a predictor of therapy response and poor prognosis in gastric cancer patients, showing higher expression correlates with worse outcomes and benefit from chemotherapy.

A target enrichment bait set for studying relationships among ostariophysan fishes

The paper designs a bait set to enrich 2,708 ultraconserved nuclear loci from ostariophysan fishes and tests its utility across various phylogenetic scales.