Author

J. Guyon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

T. Daubon· 3 shared A. Bikfalvi· 2 shared B. Klink· 2 shared T. Mathivet· 2 shared A. Burban· 1 shared A. Idbaih· 1 shared A. M. Latif· 1 shared A. Rezk· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

T. Daubon

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Author profile →

3 papers

Recent·Most cited

Exploiting a metabolic vulnerability in brain tumour stem cells using a brain-penetrant drug with safe profile

A. Burban, C. Tessier, M. Pinglaut, J. Guyon, J. Galvis, B. Dartigues, M. Toujas, M. Larroquette, H. A. Luchman, S. Weiss, N. Nicot, B. Klink, M. Nikolski, L. Brisson, T. Mathivet, , A. Sharanek

This study shows that mubritinib targets brain tumour stem cells by inhibiting complex I of the electron transport chain, delays glioblastoma tumourigenesis, and is safe in mice.

bioRxiv · Jan 15, 2024Cancer Biology

Human glioblastoma cell motility depends on the activity of the cysteine metabolism enzyme 3-Mercaptopyruvate sulfurtransferase

M. S. Saurty-Seerunghen, T. Daubon, L. Bellenger, V. Delaunay, G. Castro, J. Guyon, A. Rezk, S. Fabrega, A. Idbaih, F. Almairac, F. Burel-Vandenbos, L. Turchi, T. Virolle, J.-M. Peyrin, C. Antoniewski, , M.-P. Junier

The paper identifies MPST as a key driver of glioblastoma cell motility through oxidative stress regulation, validated using patient-derived models and in vivo experiments.

bioRxiv · Jan 21, 2022Cancer Biology

TGF-beta promotes microtube formation in glioblastoma through Thrombospondin 1

J. V. Joseph, C. R. Magaut, S. Storevik, L. H. Geraldo, T. Mathivet, A. M. Latif, J. Rudewicz, J. Guyon, M. Gambaretti, F. Haukas, A. Trones, L. A. R. Ystaas, J. A. Hossain, S. Ninzima, W. Zhou, , H. Miletic

This study identifies TGF-beta and TSP1 as key drivers of microtube formation in glioblastoma, showing their role in invasion and treatment resistance.

bioRxiv · Feb 22, 2021Cancer Biology