Author

L. Brisson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Cancer Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

G. Fromont· 2 shared T. Mathivet· 2 shared A. Bikfalvi· 1 shared A. Bokhobza· 1 shared A. Burban· 1 shared A. Fiorio Pla· 1 shared A. Folcher· 1 shared A. Haustrate· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

G. Fromont

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Author profile →

5 papers

Recent·Most cited

Protocol for open-source Automated Universal high-content multiplex fluorescence for RNA in situ Analysis (AURA)

J. Descarpentrie, F. Bernard, W. Souleyreau, L. Brisson, T. Mathivet, I. S. Pateras, O. C. Martin, M. Lopez Chiloeches, T. Frisan

The paper describes an open-source protocol for automated high-content multiplex fluorescence in situ transcriptomics analysis using Fiji macros and a Python app for data summarization.

bioRxiv · Jun 28, 2024 · PreprintCell Biology

Exploiting a metabolic vulnerability in brain tumour stem cells using a brain-penetrant drug with safe profile

A. Burban, C. Tessier, M. Pinglaut, J. Guyon, J. Galvis, B. Dartigues, M. Toujas, M. Larroquette, H. A. Luchman, S. Weiss, N. Nicot, B. Klink, M. Nikolski, L. Brisson, T. Mathivet, , A. Sharanek

This study shows that mubritinib targets brain tumour stem cells by inhibiting complex I of the electron transport chain, delays glioblastoma tumourigenesis, and is safe in mice.

bioRxiv · Jan 15, 2024Cancer Biology

Role and patterns of butterflies and hawkmoths in plant-pollinator networks at different elevations and seasons in tropical rainforests of Mount Cameroon

J. E. J. Mertens, L. Brisson, S. Janecek, Y. Klomberg, V. Maicher, S. Safian, S. Delabye, P. Potocky, I. N. Kobe, T. Pyrcz, R. Tropek

The paper quantifies the role of butterflies and hawkmoths in plant-pollinator networks across elevations and seasons in Mount Cameroon rainforests, revealing their limited overall impact but key role for specific plants.

bioRxiv · Feb 16, 2021Ecology

Expression of neuronal Na+ leak channel, NALCN, provides for persistent invasion of metastasizing cancer cells

O. Iamshanova, D. Gordienko, A. Folcher, A. Bokhobza, G. Shapovalov, D. Kannancheri-Puthooru, P. Mariot, L. Allart, E. Desruelles, C. Spriet, R. Diez, T. Oullier, S. Marionneau-Lambot, L. Brisson, S. Geraci, , N. Prevarskaya

The paper identifies NALCN as a key player in metastatic cancer cell invasion by generating Ca2+ oscillations that drive Src kinase activity and proteolytic enzyme secretion.

bioRxiv · Aug 13, 2020 · PreprintCell Biology

A comparative study of the capacity of mesenchymal stromal cell lines to form spheroids

M. Deynoux, N. Sunter, E. Ducrocq, H. Dakik, R. Guibon, J. Burlaud-Gaillard, L. Brisson, L.-R. Le Nail, O. Heraul, J. Domenech, P. Roingeard, G. Fromont, F. Mazurier

This study compares the ability of mesenchymal stromal cell lines and primary human MSCs to form spheroids, finding that cell lines form more stable spheroids over time.

bioRxiv · Nov 7, 2019Bioengineering