Author

T. Mathivet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Bikfalvi· 3 shared T. Daubon· 3 shared B. Klink· 2 shared J. Guyon· 2 shared J. Rudewicz· 2 shared L. Brisson· 2 shared L. H. Geraldo· 2 shared A. Burban· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

A. Bikfalvi

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Author profile →

5 papers

Recent·Most cited

Protocol for open-source Automated Universal high-content multiplex fluorescence for RNA in situ Analysis (AURA)

J. Descarpentrie, F. Bernard, W. Souleyreau, L. Brisson, T. Mathivet, I. S. Pateras, O. C. Martin, M. Lopez Chiloeches, T. Frisan

The paper describes an open-source protocol for automated high-content multiplex fluorescence in situ transcriptomics analysis using Fiji macros and a Python app for data summarization.

bioRxiv · Jun 28, 2024 · PreprintCell Biology

Exploiting a metabolic vulnerability in brain tumour stem cells using a brain-penetrant drug with safe profile

A. Burban, C. Tessier, M. Pinglaut, J. Guyon, J. Galvis, B. Dartigues, M. Toujas, M. Larroquette, H. A. Luchman, S. Weiss, N. Nicot, B. Klink, M. Nikolski, L. Brisson, T. Mathivet, , A. Sharanek

This study shows that mubritinib targets brain tumour stem cells by inhibiting complex I of the electron transport chain, delays glioblastoma tumourigenesis, and is safe in mice.

bioRxiv · Jan 15, 2024Cancer Biology

Emerging single cell endothelial heterogeneity supports sprouting tumour angiogenesis and growth

K. Matsumoto, F. Rambow, F. Stanchi, T. Mathivet, J. Qian, W. Giese, L. He, D. Lambrechts, B. Zhou, C. Betsholtz, J.-C. Marine, H. Gerhardt

The paper identifies a novel endothelial cell population in tumors that contributes to vascularization and growth.

bioRxiv · Jun 9, 2021 · PreprintCancer Biology

SLIT2-ROBO signaling in tumor-associated microglia/macrophages drives glioblastoma immunosuppression and vascular dysmorphia

L. H. Geraldo, Y. Xu, L. Jacob, L. Pibouin-Fragner, R. Rao, N. Maissa, M. Verreault, N. Lemaire, C. Knosp, C. Lesaffre, T. Daubon, J. Dejaegher, L. Solie, J. Rudewicz, T. Viel, , T. Mathivet

This study shows that SLIT2-ROBO signaling in tumor-associated microglia/macrophages promotes glioblastoma immunosuppression and vascular dysmorphia, and its inhibition reduces tumor growth and enhances therapy.

bioRxiv · Apr 12, 2021Cancer Biology

TGF-beta promotes microtube formation in glioblastoma through Thrombospondin 1

J. V. Joseph, C. R. Magaut, S. Storevik, L. H. Geraldo, T. Mathivet, A. M. Latif, J. Rudewicz, J. Guyon, M. Gambaretti, F. Haukas, A. Trones, L. A. R. Ystaas, J. A. Hossain, S. Ninzima, W. Zhou, , H. Miletic

This study identifies TGF-beta and TSP1 as key drivers of microtube formation in glioblastoma, showing their role in invasion and treatment resistance.

bioRxiv · Feb 22, 2021Cancer Biology