Author

J. Hakanpaeae

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

M. Galchenkova· 2 shared O. Yefanov· 2 shared A. Henkel· 1 shared A. Luana C Barra· 1 shared B. Alves Franca· 1 shared C. Schmidt· 1 shared D. Bruna Leal Oliveira· 1 shared D. Oberthuer· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

M. Galchenkova

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Author profile →

2 papers

Recent·Most cited

JINXED: Just in time crystallization for easy structure determination of biological macromolecules

A. Henkel, M. Galchenkova, J. Maracke, O. Yefanov, J. Hakanpaeae, J. R. Mesters, H. N. Chapman, D. Oberthuer

The paper introduces JINXED, a method that combines protein crystallization and data collection in one step to improve data quality and enable time-resolved experiments.

bioRxiv · Oct 26, 2022Biophysics

SARS-CoV-2 papain-like protease PLpro in complex with natural compounds reveal allosteric sites for antiviral drug design

V. Srinivasan, H. Brognaro, P. R. Prabhu, E. E. de Souza, S. Guenther, P. Y. A. Reinke, T. J. Lane, H. Ginn, H. Han, W. Ewert, J. Sprenger, F. H. M. Koua, S. Falke, N. Werner, H. Andaleeb, , P

This study identifies three natural compounds that inhibit SARS-CoV-2 PLpro by binding to the ISG15/Ub-S2 allosteric site, showing antiviral activity and potential for drug design.

Communications Biology · Aug 11, 2022Peer-reviewedBiochemistry