V. Srinivasan

Molecular Evidence of Internal Carbon-Driven Partial Denitrification Annamox (PdNA) in a mainstream Pilot A-B System Coupled with Side-stream EBPR treating municipal wastewater

This study demonstrates that a pilot-scale A-B-S2EBPR system achieves nitrite accumulation and anammox for nitrogen removal in wastewater treatment by utilizing internal carbon sources.

FosB/ΔFosB activation in mast cells regulates gene expression to modulate allergic inflammation in male mice

This study shows that FosB/ΔFosB in mast cells regulates gene expression to reduce allergic inflammation in male mice by enhancing DUSP4 expression.

Rifampicin tolerance and growth fitness among isoniazid-resistant clinical Mycobacterium tuberculosis isolates: an in-vitro longitudinal study

This study examines rifampicin tolerance in isoniazid-resistant Mycobacterium tuberculosis isolates, finding increased tolerance and faster growth in resistant strains, which may contribute to multidrug-resistant TB emergence.

Nucleoporin-binding nanobodies that either track or inhibit nuclear pore complex assembly

The paper introduces nanobodies that track or inhibit nuclear pore complex (NPC) assembly by targeting Nups and solving challenges in NPC detection and assembly inhibition.

Revisiting the role of Acinetobacter sp. in EBPR systems

The paper investigates the role of Acinetobacter in EBPR systems using 16S sequencing and SCRS-FISH, finding Acinetobacter dominance and its contribution to phosphorus removal under specific operational conditions.

SARS-CoV-2 papain-like protease PLpro in complex with natural compounds reveal allosteric sites for antiviral drug design

This study identifies three natural compounds that inhibit SARS-CoV-2 PLpro by binding to the ISG15/Ub-S2 allosteric site, showing antiviral activity and potential for drug design.

Modeling Versatile and Dynamic Anaerobic Metabolism for PAOs/GAOs Competition Using Agent-based Model and Verification via Single Cell Raman Micro-spectroscopy

This study develops and validates an improved EBPR model (iEBPR) to simulate PAO-GAO competition under extended anaerobic conditions using single-cell Raman micro-spectroscopy data.

Inhibition of SARS-CoV-2 main protease by allosteric drug-binding

The paper identifies 37 compounds binding to SARS-CoV-2 main protease through X-ray crystallography, with five non-peptidic compounds showing antiviral activity in cell-based assays.