Retrovirus-derived RTL9 plays an important role in innate antifungal immunity in the eutherian brain
F. Ishino, J. Itoh, M. Irie, A. Matsuzawa, M. Naruse, T. Suzuki, Y. Hiraoka, T. Kaneko-Ishino
The paper shows RTL9, a retrovirus-derived gene, is essential for microglial antifungal immunity by degrading fungal zymosan in the brain.
bioRxiv · Jun 29, 2023Evolutionary Biology