Y. Hiraoka

The paper shows RTL9, a retrovirus-derived gene, is essential for microglial antifungal immunity by degrading fungal zymosan in the brain.

The paper identifies the ubiquitin-proteasome pathway as a mechanism for degrading the inner nuclear membrane protein Bqt4 to maintain nuclear membrane homeostasis.

This study identifies RTL5 and RTL6 as retrovirus-derived genes involved in microglial innate immune responses against pathogens in the eutherian brain.

This study shows that Rec8 cohesin forms axis-loop structures in fission yeast meiosis, which are necessary for LinE assembly and meiotic recombination, independent of sister chromatid cohesion.

This study investigates MCM hexamer states during the cell cycle in human cells and links their formation to histone H4K20 methylation levels, showing that di/trimethyl-H4K20 correlates with double MCM hexamer formation.

This study uses live cell imaging to characterize the stable structure and dynamics of LinEs in fission yeast during meiosis.

This study reveals asymmetrical localization of the Nup107-160 subcomplex in fission yeast, contrasting with symmetrical localization in other organisms, and shows its necessity for cell cycle progression.

This study models nuclear oscillatory movements during meiosis and finds that chromosomal torsional turning, driven by directional reversals, contributes to aligning homologous chromosomes.

The paper identifies how Mto1 docks at nuclear pore complexes via Crm1 and Nup146 to form non-centrosomal MTOCs.

The paper identifies compositionally distinct nuclear pore complexes in the macronucleus and micronucleus of Tetrahymena, highlighting functional specialization through unique nucleoporin localization.