Human Vascularized Bile Duct-on-a Chip: A multi-cellular micro-physiological system for studying Primary Sclerosing Cholangitis
Y. Du, K. Gupta, O. Waisbourd-Zinman, A. Har-Zahav, C. J. Soroka, J. L. Boyer, J. Llewellyn, C. Liu, A. Naji, W. J. Polacheck, R. G. Wells
This paper develops a vascularized bile duct-on-a-chip model to study PSC, showing PSC cholangiocytes exhibit increased inflammation under IL-17A stimulation.
bioRxiv · Mar 2, 2023 · PreprintBioengineering