Characterization of SOX2, OCT4 and NANOG in ovarian cancer tumor-initiating cells
M. Robinson, S. F. Gilbert, J. A. Waters, O. Lujano-Olazaba, J. Lara, R. Holmberg, L. J. Alexander, S. E. Green, G. Burkeen, O. Patrus, C. Wang, C. D. House
This study evaluates SOX2, OCT4, and NANOG expression in ovarian cancer cell lines under 2-D and 3-D culture conditions, finding SOX2 is more strongly associated with tumor-initiating cells and chemotherapy resistance.
bioRxiv · Sep 8, 2020Cancer Biology