Author

A. Buschiazzo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 4 Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cell signaling & trafficking· 2 Assay:cryo-EM· 2 Assay:structural biology· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

F. Trajtenberg· 4 shared C. V. Sindelar· 2 shared F. San Martin· 2 shared J. A. Imelio· 2 shared K. H. Gibson· 2 shared M. Picardeau· 2 shared M. R. Brady· 2 shared A. E. Mechaly· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersMicrobiology

F. Trajtenberg

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The heme precursor 5-aminolevulinic acid triggers the shutdown of the HemKR signalling system in Leptospira

J. A. Imelio, F. Trajtenberg, S. Mondino, L. Zarantonelli, I. Vitrenko, L. Lemee, T. Cokelaer, M. Picardeau, A. Buschiazzo

This study shows that 5-aminolevulinic acid triggers shutdown of the HemKR signaling system in Leptospira by promoting HemK phosphatase activity, leading to gene expression changes and iron-deficit tolerance.

bioRxiv · Oct 19, 2023 · PreprintMicrobiology

Structural basis of flagellar filament asymmetry and supercoil templating by Leptospira spirochete sheath proteins

M. R. Brady, F. San Martin, G. E. Debs, K. H. Gibson, A. Rodriguez, R. Duran, E. Wunder, A. Ko, A. Buschiazzo, C. V. Sindelar

This study solves cryo-EM structures of Leptospira flagellar filaments, revealing how sheath proteins induce supercoiling and motility through distinct functional roles.

bioRxiv · Mar 3, 2022 · PreprintBiophysics

Molecular basis of unidirectional information transmission in two-component systems: lessons from the DesK-DesR thermosensor

S. Lima, J. Blanco, F. Olivieri, J. A. Imelio, F. Carrion, B. Alvarez, A. Buschiazzo, M. Marti, F. Trajtenberg

The paper investigates the DesK-DesR two-component system in Bacillus subtilis, revealing structural and kinetic mechanisms that enable unidirectional signal transmission.

bioRxiv · Nov 12, 2021 · PreprintBiophysics

Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel, inducing DNA-dissociation via a transmission spine

J. Lara, L. Diacovich, F. Trajtenberg, N. Larrieux, E. L. Malchiodi, M. M. Fernandez, G. Gago, H. Gramajo, A. Buschiazzo

This study reveals how M. tuberculosis FasR senses long fatty acyl-CoA through a tunnel, inducing DNA dissociation via a transmission spine.

Nature Communications · Jul 24, 2020Peer-reviewedMicrobiology

An asymmetric sheath controls flagellar supercoiling and motility in the Leptospira spirochete

K. H. Gibson, F. Trajtenberg, E. A. Wunder, M. R. Brady, F. San Martin, A. E. Mechaly, Z. Shang, J. Liu, M. Picardeau, A. I. Ko, A. Buschiazzo, C. V. Sindelar

The paper determines the structure of Leptospira flagellar filaments, revealing an asymmetric sheath that controls supercoiling and motility.

bioRxiv · Nov 21, 2019Biophysics