Author

J. Lorentzen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

H. Pedersen· 2 shared R. K. Jensen· 2 shared A. V. Almeida· 1 shared E. Tranchant· 1 shared G. R. Andersen· 1 shared G. R. R. Andersen· 1 shared H. G. Olesen· 1 shared I. B. Thoegersen· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

H. Pedersen

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Author profile →

2 papers

Recent·Most cited

Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring

T. A. Gadeberg, M. H. Joergensen, H. G. Olesen, J. Lorentzen, S. L. Harwood, A. V. Almeida, M. U. Fruergaard, R. K. Jensen, P. Kanis, H. Pedersen, E. Tranchant, S. V. Petersen, I. B. Thoegersen, J. A. Lyons, J. J. Enghild, G. R. R. Andersen

This study uses cryo-EM to analyze the structural changes in C3 during hydrolysis, revealing a dynamic opening in the macroglobulin ring that allows domain translocation.

bioRxiv · Apr 15, 2024Biochemistry

Structure of the integrin receptor M2 headpiece in complex with a function-modulating nanobody

R. K. Jensen, H. Pedersen, J. Lorentzen, N. S. Laursen, T. Vorup-Jensen, G. R. Andersen

This paper presents the atomic structure of the human Mβ2 integrin headpiece complexed with a nanobody, revealing conformational changes and functional implications for ligand binding and signaling.

bioRxiv · Jul 7, 2021 · PreprintImmunology