R. K. Jensen

This paper uses cryo-EM and ns-EM to reveal distinct conformations of IgE bound to its receptor, showing that one Fab arm is fixed while the other is flexible, and that this flexibility affects IgE function.

This paper presents the atomic structure of the human Mβ2 integrin headpiece complexed with a nanobody, revealing conformational changes and functional implications for ligand binding and signaling.

This study shows that CR3 forms a high-affinity complex with iC3b, which enhances phagocytosis and informs therapeutic development.