Author

P. Kanis

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. V. Almeida· 1 shared E. Tranchant· 1 shared G. R. R. Andersen· 1 shared H. G. Olesen· 1 shared H. Pedersen· 1 shared I. B. Thoegersen· 1 shared J. A. Lyons· 1 shared J. J. Enghild· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. V. Almeida

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1 paper

Recent·Most cited

Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring

T. A. Gadeberg, M. H. Joergensen, H. G. Olesen, J. Lorentzen, S. L. Harwood, A. V. Almeida, M. U. Fruergaard, R. K. Jensen, P. Kanis, H. Pedersen, E. Tranchant, S. V. Petersen, I. B. Thoegersen, J. A. Lyons, J. J. Enghild, G. R. R. Andersen

This study uses cryo-EM to analyze the structural changes in C3 during hydrolysis, revealing a dynamic opening in the macroglobulin ring that allows domain translocation.

bioRxiv · Apr 15, 2024Biochemistry