Author

J. Losey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

M. Moradi· 4 shared A. Polasa· 3 shared A. Abbaspourrad· 1 shared A. Cortes-Cubero· 1 shared C. Goolsby· 1 shared D. Matteson· 1 shared D. S. Matteson· 1 shared D. S. Ogden· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiophysics

M. Moradi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Computational Elucidation of Recombinant Fusion Protein Effect on Peptide-Directed Nanoparticles

A. Polasa, I. Mosleh, J. Losey, A. Abbaspourrad, R. Beitle, M. Moradi

This study uses molecular dynamics simulations to analyze how peptide sequences and their binding to GFPuv affect nanoparticle properties and free energies.

bioRxiv · Mar 11, 2021 · PreprintBioengineering

Addressing the Embeddability Problem in Transition Rate Estimation

C. Goolsby, J. Losey, Y. Xu, M.-C. Düker, M. Getmansky Sherman, D. Matteson, M. Moradi

This paper addresses the embeddability problem in transition rate estimation by proposing eight methods, including a novel approach, tested on a one-dimensional toy model.

bioRxiv · Feb 26, 2021Biophysics

Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics

J. Losey, M. Jauch, A. Cortes-Cubero, H. Wu, A. Polasa, S. Sauve, R. Rivera, D. S. Matteson, M. Moradi

The paper simulates freely-diffusing single-molecule FRET data with conformational dynamics using Langevin dynamics to test analysis techniques for flexible proteins.

bioRxiv · Jan 19, 2021 · PreprintBiophysics

Differential Dynamic Behavior of Prefusion Spike Proteins of SARS Coronaviruses 1 and 2

V. Govind Kumar, D. S. Ogden, U. Isu, A. Polasa, J. Losey, M. Moradi

This study uses molecular dynamics simulations to compare the dynamic behavior of prefusion spike proteins in SARS-CoV-1 and SARS-CoV-2, finding that SARS-CoV-2's spike is more stable with a higher energy barrier for activation.

bioRxiv · Dec 25, 2020 · PreprintBiophysics