Author

V. Govind Kumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 5 Assay:protein structure· 3 Approach:biophysical modeling· 2 Organism:human· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

M. Moradi· 5 shared T. K. Suresh Kumar· 3 shared S. Agrawal· 2 shared A. Polasa· 1 shared C. D. Heyes· 1 shared D. S. Ogden· 1 shared F. Gao· 1 shared J. Hettige· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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5 shared papersBiophysics

M. Moradi

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5 papers

Recent·Most cited

cpSRP43 is both highly flexible and stable: Structural insights using a combined experimental and computational approach

M. Benton, M. Furr, V. Govind Kumar, F. Gao, C. D. Heyes, T. K. Suresh Kumar, M. Moradi

This study investigates the structural stability and flexibility of cpSRP43 using biophysical techniques and molecular dynamics simulations, revealing it is both highly stable and flexible.

bioRxiv · Jan 11, 2022Biophysics

Binding Affinity Estimation From Restrained Umbrella Sampling Simulations

V. Govind Kumar, S. Agrawal, T. K. Suresh Kumar, M. Moradi

The paper estimates protein-ligand binding affinity using restrained umbrella sampling simulations and compares results to experimental data.

bioRxiv · Oct 28, 2021 · PreprintBiophysics

Differential Dynamic Behavior of Prefusion Spike Proteins of SARS Coronaviruses 1 and 2

V. Govind Kumar, D. S. Ogden, U. Isu, A. Polasa, J. Losey, M. Moradi

This study uses molecular dynamics simulations to compare the dynamic behavior of prefusion spike proteins in SARS-CoV-1 and SARS-CoV-2, finding that SARS-CoV-2's spike is more stable with a higher energy barrier for activation.

bioRxiv · Dec 25, 2020 · PreprintBiophysics

Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding

V. Govind Kumar, S. Agrawal, T. K. Suresh Kumar, M. Moradi

This study uses molecular dynamics simulations to show how heparin stabilizes hFGF1 by altering its conformational dynamics and electrostatic interactions.

bioRxiv · Aug 20, 2020 · PreprintBiophysics

The Role of a Crystallographically Unresolved Cytoplasmic Loop in Stabilizing the Bacterial Membrane Insertase YidC2

T. Harkey, V. Govind Kumar, J. Hettige, S. H. Tabari, K. Immadisetty, M. Moradi

The paper uses molecular dynamics simulations to show that the unresolved C2 loop in YidC2 stabilizes the protein structure and interacts with lipid head groups.

bioRxiv · Sep 13, 2019Biophysics