ImmunologybioRxiv
The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection
A. Giraud-Gatineau, J. M. Coya, A. Maure…·L. Tailleux
The paper shows that bedaquiline reprograms macrophages to enhance bactericidal activity against bacteria through metabolic and lysosomal pathways.
DOI 10.7554/elife.55692