ImmunologybioRxiv
The absence of the autoimmune regulator gene (AIRE) impairs the three-dimensional structure of medullary thymic epithelial cell spheroids
A. C. Monteleone-Cassiano, J. A. Dernowsek, R. S. Mascarenhas…·G. A. Passos
This study shows that AIRE deficiency disrupts mTEC spheroid 3D structure and alters adhesion gene regulation.
DOI 10.1186/s12860-022-00414-9