Cell BiologybioRxiv
A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability
J. B. A. Sadler, D. M. Wenzel, L. K. Williams…·J. Martin-Serrano
This paper identifies a cancer-associated polymorphism in CHMP4C that disrupts the abscission checkpoint, leading to genome instability and increased cancer risk.
DOI 10.1073/pnas.1805504115