Author

J. M. Vaz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. K. Jolly· 3 shared M. Sehgal· 2 shared A.-M. Dragoi· 1 shared C. Abshire· 1 shared H. Levine· 1 shared J. A. Somarelli· 1 shared M. Catalanotto· 1 shared M. Chu· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

M. K. Jolly

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3 papers

Recent·Most cited

Cancer BiologybioRxivAug 6, 2023

Characterizing heterogeneity along EMT and metabolic axes in colorectal cancer reveals underlying consensus molecular subtype-specific trends

M. Sehgal, S. R, J. M. Vaz…·M. K. Jolly

The paper analyzes CRC subtypes to show how EMT and metabolic axes vary across CMS subtypes, revealing subtype-specific metabolic and mesenchymal correlations.

DOI 10.1016/j.tranon.2023.101845

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 12, 2023

Dual role of CASP8AP2/FLASH in regulating epithelial-to-mesenchymal (EMT) plasticity

M. Catalanotto, J. M. Vaz, C. Abshire…·A.-M. Dragoi

This study identifies FLASH as a regulator of EMT plasticity, showing it influences hybrid E/M states through its effects on EMT-TFs and cell junction proteins.

DOI 10.1101/2023.03.12.532282

humanstatistical model

𝕏 PostBluesky

Cancer BiologybioRxivAug 20, 2022

Partial EMT and associated changes in cellular plasticity in oncovirus-positive samples

M. Sehgal, R. Ray, J. M. Vaz…·M. K. Jolly

The paper analyzes transcriptomics data to identify common gene regulatory features in oncovirus-positive samples, revealing partial EMT and metabolic changes linked to immune checkpoint molecules.

DOI 10.1016/j.adcanc.2023.100091

humanbulk RNA-seq

𝕏 PostBluesky