P. Katajisto

This study shows that autophagy regulates asymmetric inheritance of old mitochondria in CD8+ T cells, which influences their metabolic state and memory potential.

This study shows that the N-terminal fragment of α-dystroglycan blocks SARS-CoV-2 and other enveloped viruses in cell culture and animal models.

This study shows that Lgr5+ stem cells in the small intestine adjust their Golgi apparatus orientation to enhance niche signal reception and tissue regeneration, which is impaired with age.

The paper identifies a shared genomic region upstream of Myc that is critical for both intestinal regeneration and cancer, revealing a genetic link between tissue renewal and tumorigenesis.

The paper shows that flat clathrin lattices assemble reticular adhesions, which are opposed by fibrillar adhesions, revealing a novel interaction between endocytic and adhesion processes.

The paper introduces LAM, an imaging method to analyze regional cellular phenotypes in Drosophila midgut, revealing regional heterogeneity in ISC responses to colitis.

The paper identifies MMP17 as a smooth muscle-specific factor critical for intestinal epithelial repair and stem cell niche regulation through its cleavage of PERIOSTIN and activation of YAP.

This study shows that laminin alpha 5 is essential for mammary gland growth and function by maintaining luminal epithelial cell identity during development and remodeling.