Cancer BiologybioRxiv
Classes of ITD predict outcomes in patients with AML treated with FLT3 inhibitors
G. W. Schwartz, B. Manning, Y. Zhou…·R. Faryabi
The paper classifies FLT3-ITD mutations into typical and atypical based on nucleotide composition and shows typical ITD carriers have better outcomes with FLT3 inhibitors.
DOI 10.1158/1078-0432.ccr-18-0655