Author

J. N. Bazil

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

E. V. Pavlov· 1 shared J. F. Conway· 1 shared J. O. Strubbe· 1 shared J. R. Schrad· 1 shared K. N. Parent· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

E. V. Pavlov

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1 paper

Recent·Most cited

Cell BiologyScientific ReportsPeer-reviewedJan 13, 2021

The Mitochondrial Permeability Transition Phenomenon Elucidated by Cryo-EM Reveals the Genuine Impact of Calcium Overload on Mitochondrial Structure and Function

J. O. Strubbe, J. R. Schrad, E. V. Pavlov…·J. N. Bazil

The study uses cryo-EM to show how calcium overload causes mitochondrial permeability transition by forming calcium phosphate granules and inner membrane fragmentation, and reveals cyclosporin A's role in preserving inner membrane structure.

DOI 10.1038/s41598-020-80398-8

imagingexperimental assay

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