BiochemistrybioRxiv
Substrate selectivity of the PRDM9 lysine methyltransferase domain.
J. N. Hanquier, K. Sanders, C. A. Berryhill…·E. M. Cornett
This study identifies PRDM9's substrate selectivity, showing it preferentially methylates non-histone proteins over histones, with structural and biochemical validation.
DOI 10.1016/j.jbc.2023.104651