BiochemistrybioRxiv
Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations
A. Kafkova, L. Tilokani, F. Trcka…·J. Trnka
This study shows alkyl-TPP reversibly alters mitochondrial morphology and function, selectively decreasing inner membrane proteins and cleaving Optic atrophy-1, with effects not due to membrane potential loss.
DOI 10.1016/j.mito.2022.11.006