Author

J. Östblom

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

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A. Keller· 1 shared C. Markouli· 1 shared C. Spits· 1 shared D. Dziedzicka· 1 shared E. Couvreu De Deckersberg· 1 shared F. Van Nieuwerburgh· 1 shared K. Sermon· 1 shared L. Prochazka· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperCell Biology

A. Keller

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1 paper

Recent·Most cited

Cell BiologybioRxivJul 3, 2020

Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm

D. Dziedzicka, M. Tewary, A. Keller…·M. Geens

The paper shows that endogenous suppression of WNT signaling in hPSCs reduces differentiation efficiency towards definitive endoderm, and that increasing WNT or inhibiting PI3K/AKT can overcome this block.

DOI 10.1038/s41598-021-85447-4

humanbulk RNA-seq

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