BiochemistrybioRxiv
A quantitative and predictive model for RNA binding by human Pumilio proteins
I. Jarmoskaite, S. K. Denny, P. P. Vaidyanathan…·D. Herschlag
The paper develops a predictive model for RNA binding by human PUM1 and PUM2 using RNA-MaP data, showing residue flipping and positional coupling, and validates it against in vivo crosslinking data.
DOI 10.1016/j.molcel.2019.04.012