BioengineeringbioRxiv
Increased biosynthesis of acetyl-CoA in the yeast Saccharomyces cerevisiae by overexpression of a deregulated pantothenate kinase gene
J. Olzhausen, M. Grigat, L. Seifert…·H.-J. Schueller
This paper identifies a hyperactive pantothenate kinase variant in yeast that, when overexpressed with other CoA biosynthesis genes, increases CoA nucleotides 15-fold.
DOI 10.1007/s00253-021-11523-4