Author

J. P. Hanley

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Biochemistry· 1

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

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B. L. Carroll· 1 shared J. A. Dragon· 1 shared K. E. Zahn· 1 shared S. Doublie· 1 shared S. S. Wallace· 1 shared

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2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

B. L. Carroll

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1 paper

Recent·Most cited

BiochemistrybioRxivAug 13, 2021

Caught in Motion: Human NTHL1 Undergoes Interdomain Rearrangement Necessary for Catalysis

B. L. Carroll, K. E. Zahn, J. P. Hanley…·S. Doublie

This study reports the first X-ray structure of human NTHL1, revealing an open conformation essential for catalysis and showing that interdomain rearrangement is critical for DNA binding.

DOI 10.1093/nar/gkab1162

humanstructural biology

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