Author

J. P. Ochoa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein sequence· 1 Assay:structural biology· 1

Frequent Co-Authors

D. Velazquez-Carreras· 2 shared E. Herrero-Galan· 2 shared F. Dominguez· 2 shared I. Martinez-Martin· 2 shared P. Garcia-Pavia· 2 shared A. Briceno· 1 shared A. Crousilles· 1 shared A. Fernandez-Trasancos· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiochemistry

D. Velazquez-Carreras

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2 papers

Recent·Most cited

BiochemistrybioRxivJun 2, 2023

Amino acid substitutions hydrophilizing the core of titin domains cause dilated cardiomyopathy

I. Martinez-Martin, A. Crousilles, J. P. Ochoa…·J. Alegre-Cebollada

The paper identifies amino acid substitutions in titin domains that increase hydrophilicity and cause dilated cardiomyopathy by destabilizing the protein structure.

DOI 10.1016/j.celrep.2023.113490

humanstructural biology

𝕏 PostBluesky

PhysiologybioRxivSep 5, 2020

Conserved cysteines in titin sustain the mechanical function of cardiomyocytes

E. Herrero-Galan, F. Dominguez, I. Martinez-Martin…·Aleg

The paper identifies that mutations in conserved titin cysteines disrupt mechanoredox control, leading to dilated cardiomyopathy in humans.

DOI 10.1016/j.redox.2022.102306

humanprotein sequence

𝕏 PostBluesky