Author

J. P. Reddington

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Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

C. Girardot· 2 shared P. Khoueiry· 2 shared D. A. Garfield· 1 shared E. E. M. Furlong· 1 shared E. Furlong· 1 shared J. Liu· 1 shared M. Robinson-Rechavi· 1 shared P.-C. Peng· 1 shared

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2018-2020 · peak 1/yr

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10 top collaborators · 29 mutual co-author links

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2 shared papersEvolutionary Biology

C. Girardot

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2 papers

Recent·Most cited

Evolutionary BiologybioRxivNov 2, 2020

The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection

J. Liu, R. R. Viales, P. Khoueiry…·M. Robinson-Rechavi

The paper identifies a higher proportion of conserved enhancers during the phylotypic period of Drosophila embryogenesis and detects positive selection on enhancers at early and late stages.

DOI 10.1101/gr.275212.121

DrosophilaChIP-seq

𝕏 PostBluesky

Evolutionary BiologybioRxivOct 15, 2018

The role of chromatin accessibility in cis-regulatory evolution

P.-C. Peng, P. Khoueiry, C. Girardot…·S. Sinha

This study examines how chromatin accessibility and sequence changes influence the evolutionary divergence of transcription factor binding in Drosophila species.

DOI 10.1093/gbe/evz103

DrosophilaATAC-seq

𝕏 PostBluesky