Comparative evaluation of glomerular morphometric techniques reveals differential technical artefacts between FSGS and normal glomeruli
J. M. Basgen, A. C. Reghuvaran, Q. Lin, K. Banu, H. Shi, J. Pell, J. DiRito, G. T. Tietjen, S. Perincheri, D. G. Moledina, F. P. Wilson, M. C. Menon
This study evaluates glomerular morphometric techniques, finding that 10-glomerular sampling is sufficiently precise and that paraffin-embedding causes shrinkage bias affecting FSGS and normal glomeruli differently.
bioRxiv · Feb 15, 2022 · PreprintPathology